Biopolymers publishes original research papers and review articles in the general area of macromolecular structure and function, as well as biologically relevant model systems. Manuscripts should report on studies that examine biological macromolecules (naturally occurring and designed), their interactions, reactions, and macromolecular assemblies at structural, chemical, and physical levels. The Journal strives to publish high-impact papers that will significantly enhance our understanding of the chemistry and/or the biology of the systems under investigation. Reports describing techniques that could be applied to the study of biological macromolecules will be considered for publication only if they will have broad utility to the biochemical and biophysical research community.Topics of particular interest include, but are not limited to:Molecular recognition; multi-component complexes and macromolecular assembly, including ordered aggregationMolecular design, biomimics, model systems, and bio-nanotechnologyBiopolymer processing and degradationExperimental and theoretical studies of biopolymer foldingSingle molecule studies of biopolymers (e.g., fluorescence, optical tweezers, AFM, etc.)Three-dimensional structures of biopolymers determined by X-ray, NMR, EM, other spectroscopic methods, as well as computational predictionBioenergetics of macromolecules and their interactionsUse of small molecules as either probes or models of structure and function, or as ligands that target biologically relevant receptorsPreparation and characterization of novel biomaterialsFunction may include:DNA recombination, replication and repairCatalysisMolecular motorsIntracellular signaling and signal transductionChromatin structure and remodelingRNA processingTranscriptionTranslationProtein/RNA sorting and trafficking

生物聚合物在大分子結構和功能以及生物相關的模型系統的一般領域發表原始的研究論文和評論文章。手稿應報告研究生物大分子(自然發生和設計)，他們的相互作用，反應，和大分子組裝在結構，化學和物理水平。該雜志致力于發表高影響力的論文，將顯著提高我們對所研究系統的化學和/或生物學的理解。描述可應用于生物大分子研究的技術的報告只有在對生物化學和生物物理研究領域具有廣泛用途時才會考慮發表。特別感興趣的題目包括但不限于:分子識別;多組分配合物和大分子組裝，包括有序聚集分子設計，仿生學，模型系統，生物納米技術生物聚合物的加工和降解生物高分子折疊的實驗與理論研究生物聚合物的單分子研究(如熒光、光鑷、AFM等)生物聚合物的三維結構由x射線、NMR、EM等光譜方法測定，以及計算預測大分子的生物能學及其相互作用利用小分子作為探針或結構和功能的模型，或作為靶向生物學相關受體的配體新型生物材料的制備與表征功能可能包括:DNA重組，復制和修復催化分子馬達細胞內信號和信號轉導染色質結構和重塑RNA加工轉錄翻譯蛋白質/RNA的分類和運輸